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Expert Interview

Slingshot members are talking to an expert! The topic is:

Discussing DVAX' HEPLISAV-B vaccine and market potential post approval

Ticker(s): DVAX, GSK

Who's the expert?

An infectious disease expert with experience treating patients that have HEP-B, as well as vaccinating people with GSK's Engerix-B

Interview Questions
Q1.

Can you give us an idea of the Hep-B vaccine market now, what types of patients get vaccinated and how well covered people are currently?

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Q2.

Please give us a little information about your background in Hep-B.

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Q3.

What is your impression to the Phase 3 data released by Dynavax?

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Q4.

What is the current standard of care for high risk populations, like diabetics, elderly and obese patients? How do you see HEPLISAV-B changing this paradigm?

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Q5.

Is Bells Palsy a side effect associated with current adult hepatitis B vaccines (Engerix)? How would a two dose regimen over 4 weeks impact compliance versus a three dose regimen over 6 months in the typical target patient in your opinion?

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Q6.

What can you tell us about compliance among diabetics since ACIP's recommendation re: hep b vaccination four years ago? If low, is this an education issue? Compliance issue? Other?

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Q7.

Do you see the data for HEPLISAV-B being compelling enough that you would switch from using Engerix-B to HBV-23 if it was approved?

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Q8.

How much would a two dose regimen over one month improve compliance vs. the three dose regimen over 6 months in your opinion?

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Q9.

How would you view a premium price for HEPLISAV-B, considering the potential compliance improvements?

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