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Expert Interview

Slingshot members are talking to an expert! The topic is:

An updated look at Nektar Therapeutics’ Phase 2b REZOLVE-AA study results evaluating rezpegaldesleukin in patients with severe-to-very-severe alopecia areata

Ticker(s): NKTR

Who's the expert?

Institution: Harvard Medical School

  • Associate Professor of Dermatology at Harvard Medical School and Vice Chair of Clinical Trials and Innovation at Brigham and Women’s Hospital

  • Currently manages over 150 patients with alopecia areata.

  • Reseaarch focus on alopecia areata, complex medical dermatology, diagnostic testing, and health disparities.

Interview Questions
Q1.

What is your overall interpretation of the Phase 2b REZOLVE-AA results for rezpegaldesleukin in severe-to-very-severe alopecia areata, and what do you view as the key clinical takeaways?

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Q2.

How meaningful were the observed hair regrowth outcomes (e.g., SALT response thresholds) in the context of severe AA, and how do these results compare with what you see with current standards of care (including JAK inhibitors)?

Added By: sara_admin
Q3.

What safety/tolerability considerations matter most for long-term AA therapy, and based on the Phase 2b profile, what stands out to you as either reassuring or concerning?

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