Expert Interview
A look at the Phase 1b/2 DURGA-1 study results presented at ASH evaluating AZD0120, AstraZeneca’s dual BCMA/CD19 CAR T-cell therapy for relapsed/refractory multiple myeloma
Ticker(s): AZNInstitution: Washington University St. Louis
- Professor Department of Medicine Oncology Division Bone Marrow Transplantation & Leukemia at WUSTL
- Currently treats ~300 patients with multiple myeloma, 25 patients with AML, 10 patients with CMML, and ~15 patients per month with AL Amyloidosis.
- Clinical research focus on strategies to improve the outcome of patients with multiple myeloma, acute myeloid leukemia, and myelodysplastic syndromes.
From your perspective, what differentiates AZD0120’s dual BCMA/CD19 CAR T-cell construct from currently approved single-target BCMA CAR T therapies in relapsed/refractory multiple myeloma?
Added By: sara_adminHow do you interpret the efficacy signals reported in the Phase 1b/2 DURGA-1 study, particularly in heavily pretreated or high-risk patient populations?
Added By: sara_adminDo you see dual-target CAR T approaches like AZD0120 as a meaningful strategy to address antigen escape and durability of response in multiple myeloma?
Added By: sara_adminAre You Interested In These Questions?
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