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Expert Interview

Slingshot members are talking to an expert! The topic is:

Looking at the Recent FDA Approval for GSK’s Blenrep (belantamab mafodotin-blmf) Combination Therapy for Relapsed/Refractory Multiple Myeloma

Ticker(s): GSK

Who's the expert?

Institution: Mayo Clinic

  • Professor of Medicine in the Division of Hematology/Oncology at the Mayo Clinic Florida
  • Manages 50 patients with Waldenström's macroglobulinemia and can speak to the data available for iopofosine and the CLOVER-WaM study.
  • Clinical focus includes the treatment of plasma cell disorders, multiple myeloma (MM), Waldenström's macroglobulinemia, and chronic lymphocytic leukemia (CLL).

Interview Questions
Q1.

Do you anticipate broader adoption of Blenrep in community oncology settings, given its accessibility versus other BCMA-directed therapies (e.g., CAR-T, bispecifics)?

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Q2.

Given Blenrep’s known ocular toxicity profile, how do you view the updated REMS program? Does the streamlined approach meaningfully reduce barriers to use in clinical practice?

Added By: sara_admin
Q3.

Where do you see Blenrep + bortezomib/dexamethasone fitting in the current treatment sequence for patients who have received at least two prior lines of therapy?

Added By: sara_admin
Q4.

Are there specific patient types, based on prior therapies, cytogenetics, or comorbidities, who you believe may particularly benefit from the Blenrep combination?

Added By: sara_admin

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