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Expert Interview

Slingshot members are talking to an expert! The topic is:

Discussing current commercial use of Ayvakit and the ongoing SUMMIT trial evaluating bezuclastinib in iSM (indolent systemic mastocytosis)

Ticker(s): COGT, BPMC

Who's the expert?

Institution: Scripps Clinic

  • Allergist/Immunologist & Director, Aspirin Exacerbated Respiratory Disease Clinic,Division of Allergy, Asthma and Immunology at the Scripps Clinic.
  • Currently manages 35 patients with systemic mastocytosis.
  • Focus is on Aspirin exacerbated respiratory disease (AERD), mastocytosis, and mast cell activation syndromes; conducts research on aspirin exacerbated respiratory disease, a topic on which he has authored multiple publications and ongoing research protocols.

Interview Questions
Q1.

How many iSM patients do you have on Ayvakit?

Added By: wilson_admin
Q2.

How concerning is the AE profile seen in bezuclastinib, in particular the liver signal and diarrhea?

Added By: wilson_admin
Q3.

What would you need to see in the SUMMIT trial to justify use of bezuclastinib over Ayvakit?

Added By: wilson_admin

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Reason

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