Expert Interview
A look at the long-term data from Xenon Pharmaceuticals’ X-TOLE study evaluating azetukalner in patients with focal onset seizures.
Ticker(s): XENEInstitution: Yale University
- Professor of Clinical Neurology and Interim director of Epilepsy Monitoring Unit at Yale Medical School
- Treats 500 adult patients with epilepsy and 600 patients with focal onset seizures per year
- Research interest in new therapies for epilepsy using anticonvulsant medications and devices to treat patients with refractory epilepsy, neuromodulation, surgical treatment of seizure disorders, invasive electroencephalogram (EEG) techniques, intracranial EEG, and intraoperative EEG mapping.
1. Based on the long-term data from the X-TOLE OLE study, how do you interpret the durability of response and safety profile of azetukalner for managing focal onset seizures?
3. In your clinical experience, what are the key unmet needs in treating focal onset seizures, and do you see azetukalner addressing any of these gaps based on the current data?
2. How might the mechanism of action of azetukalner as a potassium channel opener differentiate it from other antiseizure medications currently available?
Added By: sara_adminIn your clinical experience, what are the key unmet needs in treating focal onset seizures, and do you see azetukalner addressing any of these gaps based on the current data?
Added By: sara_adminAre You Interested In These Questions?
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