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Expert Interview

Slingshot members are talking to an expert! The topic is:

A Second Look: Discussing Ipsen's Phase 3 data from the ELMWOOD study of elafibranor in patients with primary sclerosing cholangitis (PSC).

Ticker(s): IPSEY, IPN.XPAR

Who's the expert?

Institution: Yale University

  • Academic hepatologist, Associate Professor of Medicine (Digestive Diseases) and Director, Yale Viral Hepatitis Program.
  • Treats patients with chronic liver diseases including the entire spectrum from cirrhosis, liver failure, and post-transplant; Approximately 5-10% of his patients have chronic pruritus symptoms, 200 patients with biopsy-proven NASH and a larger cohort of NAFLD, and 70 patients with PBC/PSC.
  • Has served on the national steering committees for large observational cohort studies for liver disease and has published over 100 papers in the area of GI and liver diseases.

Interview Questions
Q1.

How frequently do you manage or consult on cases of primary sclerosing cholangitis (PSC) in your clinical practice?

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Q2.

Can you discuss elafibranor’s mechanism of action and its potential therapeutic role in cholestatic liver diseases like PSC?

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Q3.

Based on the available data, how would you compare elafibranor’s efficacy and safety profile to other investigational therapies or off-label treatments currently used for PSC?

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