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Survey

Slingshot members are conducting a survey! The topic is:

Two Week Delay: Survey on GERN’s Rytelo (imetelstat) and MDS April 2025

Ticker(s): GERN

Who's being surveyed?

The survey includes 20 Hematologists/Oncologists.

Survey Questions
Q1.

How many lower risk MDS patients do you see?

Q2.

How many patients have you prescribed Rytelo (imetelstat) to date?

Q3.

What is your view on the overall profile of Rytelo (imetelstat)?

Q4.

What profile of patient is a good candidate for Rytelo (imetelstat)?

Q5.

Would you use Rytelo (imetelstat) before or after Reblozyl (luspatercept) in RS- patients?

  • Before:
  • After:
  • Other:

Q6.

What percentage (%) of patients who would otherwise be candidates for Rytelo (imetelstat) are unable to start due to a contraindication (baseline cytopenias, liver enzyme elevations, etc.)?

Q7.

Anecdotally, how do your patients feel on Rytelo (imetelstat) compared to Reblozyl (luspatercept)?

Q8.

What is the biggest barrier to using Rytelo (imetelstat)?

Q9.

Please indicate the number of low-risk MDS patients (RS+) you currently have on each of the following treatments. Also, provide your projected patient counts for each treatment 1 year and 5 years from now.

  • Now
    • # on imetelstat
    • # on luspatercept
    • # on other therapies

  • 1 year:
    • # on imetelstat
    • # on luspatercept
    • # on other therapies

  • 5 years:
    • # on imetelstat
    • # on luspatercept
    • # on other therapies

Q10.

Please indicate the number of low-risk MDS patients (RS-) you currently have on each of the following treatments. Also, provide your projected patient counts for each treatment 1 year and 5 years from now.

  • Now
    • # on imetelstat
    • # on luspatercept
    • # on other therapies

  • 1 year:
    • # on imetelstat
    • # on luspatercept
    • # on other therapies

  • 5 years:
    • # on imetelstat
    • # on luspatercept
    • # on other therapies

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