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Expert Interview

Slingshot members are talking to an expert! The topic is:

Discussing the Phase 3 Tenapanor results in Hyperphosphatemia for patients with CKD on dialysis.

Ticker(s): ARDX, KERX

Who's the expert?

Name: Dr Kamyar Kalantar-Zadeh - MD

Institution: UC Irvine

  • Chief, Division of Nephrology, Hypertension and Kidney Transplantation at UC Irvine.
  • Known for his hypothesis about the longevity of individuals with chronic kidney disease states, also known as reverse epidemiology including obesity paradox.
  • Specializes in kidney dialysis therapy, including incremental dialysis, and renal nutrition.  

Interview Questions
Q1.

Please describe your clinical practice and how many patients with Hyperphosphatemia you see monthly.

Added By: joe_mccann
Q2.

How do you currently manage these patients?

Added By: joe_mccann
Q3.

Does the mechanism of action for Tenapanor appeal to you? What are the current short coming of the phosphate binders. 

Added By: joe_mccann
Q4.

Looking at the top-line results in this press release what are your views on the efficacy seen?

Added By: joe_mccann
Q5.

Turning to side effects, can you put the discontinuation rate of 7.8% for GI issues for the Tenapanor group in context for us? What do you make of that number?

Added By: joe_mccann
Q6.

How much switching due to tolerability do you currently see in this patient population? What other reasons do patients switch or discontinue a treatment.

Added By: joe_mccann

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