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Expert Interview

Slingshot members are talking to an expert! The topic is:

Discussing Incyte's Phase 3 results for Povorcitinib in Patients With Hidradenitis Suppurativa.

Ticker(s): INCY

Who's the expert?

Institution: UT Dell Medical School

  • Board certified dermatologist and assistant profess at UT Dell Medical School. 
  • Serves as cheif of dermatology at Central Texas Veterans Health Care System.
  • Clinical expertise in medical and surgical treatment of hidradenitis suppurativa and is the head of the Follicular Disorders Clinic in Austin.
  • Completed her internship in pediatrics at St. Christopher’s Hospital for Children in Philadelphia followed by residency training in dermatology at Henry Ford Health System in Detroit.

Interview Questions
Q1.

How many patients do you manage with for Hidradenitis Suppurativa?

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Q2.

On a scale from 1-10 (10 being extremely excited), how excited are you about the Phase 2 results for Povorcitinib?

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Q3.

Now that topline Phase 3 data is available, how would you describe your level of confidence in povorcitinib becoming a viable treatment option for moderate to severe HS?

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Q4.

Were you surprised by the consistency of efficacy across both STOP-HS1 and STOP-HS2 trials at both the 45 mg and 75 mg doses? Why or why not?

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Q5.

The studies showed  improvements in HiSCR50 and also deeper responses like HiSCR75 and skin pain reduction. How important are these endpoints to you in clinical practice?

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Q6.

Given the safety profile and oral administration of povorcitinib, how do you see this treatment fitting into your current HS management approach—especially for patients who have failed biologics?

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Q7.

With a potential regulatory submission underway, what factors would influence your willingness to adopt povorcitinib quickly after approval?

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