Expert Interview
A Second Opinion: Reviewing the potential of AAV-GAD, a gene therapy from MeiraGTx for the treatment of Parkinson's Disease
Ticker(s): MGTXInstitution: Montefiore Medical Center
- Director, Division of Movement Disorders and Assistant professor of Neurology at Albert Einstein College of Medicine
- Sees 220 patients with Parkinson's Disease yearly
- Clinical interest and contributor to journal articles and book chapters on a variety of neurologic topics
How many patients do you manage with Parkinson's?
Added By: ben_adminWhat are your thoughts on the potential of AAV-GAD?
Added By: ben_adminDescribe your background and current practice setting. How many patients with PD do you manage?
Added By: ben_adminWhat are the current treatment options for Parkinson's disease, and how effective are they in managing symptoms, especially as the disease progresses?
Added By: catalin_adminWhat are the primary unmet needs in Parkinson's treatment, and could gene therapy like AAV-GAD fulfill these gaps by altering the disease's progression or providing new symptomatic relief?
Added By: catalin_adminHow does the administration of AAV-GAD (bilateral infusion into the subthalamic nucleus) compare to deep brain stimulation (DBS) in terms of procedure complexity, patient perception, and potential barriers?
Added By: catalin_adminWhat are the safety and tolerability concerns related to AAV-GAD, and what kind of data or longer-term effects would experts like to see in future trials to ensure its viability?
Added By: catalin_adminWho would be considered the ideal candidate for AAV-GAD, and what factors would influence the choice between this gene therapy and existing treatments like DBS?
Added By: catalin_adminAre You Interested In These Questions?
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