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Expert Interview

Slingshot members are talking to an expert! The topic is:

A second look: Discussing Rezdiffra and various investigational agents in MASH

Ticker(s): MDGL, AKRO, ETNB

Who's the expert?

Institution: Texas Liver Institute

  • Medical Director and VP of Research and Development at the Texas Liver Institute and Professor of Medicine at the University of Texas Health San Antonio.
  • Manages hundreds of patients with NASH.
  • Has authored over 400 peer-reviewed publications in medical journals.

Interview Questions
Q1.

What are your high-level thoughts on the competitive landscape of GLP-1 drugs in development for NASH, and how are NASH products evolving in the market?

Added By: slingshot_insights
Q2.

How do you expect the fibrosis impact from semaglutide to compare with other drugs like resmetirom, and what are your expectations for its clinical outcomes?

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Q3.

Assuming semaglutide shows a fibrosis improvement, how will this affect the commercial use of resmetirom and other NASH therapies such as FGF21s?

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Q4.

How do you envision the treatment of NASH and MASH evolving over the next five years, particularly regarding polypharmacy and monotherapy with drugs like GLP-1s, FGF21s, and pan-PPARs?

Added By: slingshot_insights
Q5.

In the hepatitis B treatment landscape, what are your views on emerging antiviral therapies, the role of CAM inhibitors, and the future of immune-based therapies like PD-1s?

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