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Expert Interview

Slingshot members are talking to an expert! The topic is:

Discussing the appropriate use and future of Pluvicto Radionuclide Therapy amidst the developing treatment landscape for genitourinary cancers.

Ticker(s): NVS, FUSN, RYZB, PNT

Who's the expert?

Institution: University of Minnesota (formerly Hopkins)

  • Associate Director for Translational Research at the Masonic Cancer Center & Director of Genitourinary Oncology Hematology, Oncology, and Transplantation) at the University of Minnesota Medical School.
  • Clinical interest is the management of prostate cancer and other genitourinary malignancies. 
  • Research focuses on developing novel androgen-directed therapies, genetically-targeted therapies, and immunotherapies for men with recurrent or advanced prostate cancer, and using germline and cancer genomics to inform precision oncology approaches. 

Interview Questions
Q1.

Can you explain the pros and cons of specific approaches to radioligand therapies such as; using antibodies, small molecules, or other targeting moieties?

Added By: sara_admin
Q2.

Any thoughts on how Bristol Myers Squibb's acquisition of Rayze Bio will be impactful to the radiopharmaceutical industry?

Added By: sara_admin
Q3.

Can you discuss which actinium based radiotherapies in development most excite you?

Added By: sara_admin
Q4.

For actinium therapies, what would be an acceptable rate of salivary gland toxicity? Would Grade 3 or higher events give you pause in using in Post-Lu patients?

Added By: mattgamber
Q5.

What would need to happen to bring Ac therapies to an earlier line setting, even before Lu therapies?

Added By: mattgamber
Q6.

Where do you see the total addressable market for Lu and Ac therapies ultimately settling in at with radiopharmaceuticals receiving more uptake and awareness?

Added By: mattgamber

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Reason

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