This project has been flagged by a community member as inappropriate due to reason below.*

Expert Interview

Slingshot members are talking to an expert! The topic is:

A Third View: Discussing acoramidis and part B of the ATTRibute trial in ATTR-CM (Transthyretin Amyloid Cardiomyopathy)

Ticker(s): BBIO, PFE, ALNY

Who's the expert?

Institution: University of Colorado
  • Director of Cardiac Amyloidosis & Cardiac Transplantation program and Associate Professor, Medicine-Cardiology at the University of Colorado. 
  • Currently manages ~60 active ATTR cardiac amyloid patients and has prescribed Tafamidis.
  • Research focuses on Cardiac Amyloidosis, Advanced Heart Failure, Cardiac Transplantation, and Mechanical Circulatory Support / Ventricular Assist Devices; has participated in multiple clinical trials investigating new pharmacologic and device therapies for patients with advanced heart failure and cardiac amyloidosis. 

Interview Questions

why do you think Part A of ATTRibute failed?

Added By: wilson_admin

What do you think of the Part B probability of success?

Added By: wilson_admin

How do you view acoramidis compared to other options

Added By: wilson_admin

Thinking of the three entrants into the CM arena - vutrisiran, eplontersen, and acoramidis, characterize what you believe are the differentiating advantages/disadvantages of each?

Added By: wilson_admin

Describe how you see the marketing shaking out with the emergence of three different players with three different solutions (vutrisiran, eplontersen, and acoramidis) in the aTTR-CM market? Are there unique patient types for each?

Added By: wilson_admin

What do you think the win ratio will be for ATTRibute-CM?

Added By: wilson_admin

In ATTR-ACT, the greatest benefit seemed to be in NYHA 1-2 irrespective of wt or m — that suggests that earlier disease responds better. Since the hypothesis is that ATTRibute-CM has a left-shifted population, should we expect a higher win ratio with AG10? 

Added By: wilson_admin

Are You Interested In These Questions?

Slingshot Insights Explained

Expert research benefits investors by giving them timely access to unbiased real world perspectives on highly specialized topics. Slingshot Insights' crowdfunded model makes this access available at a fraction of the cost of other expert networks.


*Slingshot Insights provides access to information, not investment advice. We work to support you and facilitate access to experts; however we are not responsible for monitoring calls for the disclosure of MNPI. You should obtain financial, legal and tax advice from your qualified and licensed advisers before deciding to invest in any security.