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Expert Interview

Slingshot members are talking to an expert! The topic is:

A Second Look: Examining the IPF treatment landscape with a focus on Pliant's bexotegrast, Fibrogen's pamrevlumab, and United Therapeutics' TYVASO (treprostinil)

Ticker(s): FGEN, PLRX, UTHR

Who's the expert?

Institution: National Jewish Health

  • Associate Professor in the Department of Medicine and Clinic Director of the Interstitial lung disease(ILD) Program at National Jewish Health.
  • Sub-investigator for the Phase II study for PLN 74809 as well as numerous other ILD/IPF studies being conducted at National Jewish Health.
  • Research focuses on biomarkers in ILD and exercise limitation in post-COVID syndrome, with past research focused on investigating the role of angiogenesis in resolving lung injury and fibrosis. 

Interview Questions
Q1.

How do each of these three treatments differ in their mechanism of action and do any of them stand out to you as a preferred method?

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Q2.

Pliant Therapeutics is developing bexotegrast, which works on a different target from the approved drugs. What are your thoughts on this target and the data that they have generated so far?

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Q3.

What are your thoughts on bexotegrast target and the data that they have generated so far?

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Q4.

How would you describe the current standard of care, the available treatments and the unmet needs in this space?

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