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Expert Interview

Slingshot members are talking to an expert! The topic is:

Comparing EyePoint's EYP-1901 and 4D Molecular Therapeutics' gene therapy, 4D-150 for the treatment of wet-AMD

Ticker(s): EYPT, REGN, FDMT

Who's the expert?

Institution: Retina Associates of New York

  • Private practice ophthalmologist who also trains doctors at the New York Eye and Ear Infirmary of Mount Sinai.
  • Currently manages between 200-300 patients with wet-AMD and 200 with geographic atrophy.
  • Has authored multiple peer-reviewed publications, including research on macular degeneration, diabetic retinopathy, macular pucker, and unusual diseases of the retina.

Interview Questions
Q1.

Please describe your background and current practice setting

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Q2.

How many patients with macular edema do you currently treat monthly?

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Q3.

Can you break down your treatment algorithm? What are you using in the first and second line for these indications?

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Q4.

What were your overall impressions of Eyepoint's phase 1 data for treatment of patients with wet-AMD? Of 4D's gene therapy?

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Q5.

Please rank your excitement for Eyepoint's EYP-1901 and 4D Molecular Therapeutics 4D-150 on a scale of 1-10

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Q6.

When 4D announces its wet-AMD data on all 15 pa at ARVO 23, what specific data would you like to see to conclude this program is best in class?  

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Q7.

What efficay, safety profile, and duration of response do you need to see from a gene therapy treatment to prescribe it broadly in practice?  What % of wetAMD patients in your practice would you likely treat with gene therapy? 

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Q8.

Do you have any relationship with EYPT or FDMT?

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Q9.

What are your thoughts around neuroprotection and fibrosis?  

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