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Expert Interview

Slingshot members are talking to an expert! The topic is:

Digging into the Phase 1 data on Affimed's AFM24 and atezolizumab combination in patients with EGFR+ solid tumors

Ticker(s): AFMD

Who's the expert?

Institution: Advanced Care Oncology And Hematology Associates

  • Medical Oncologist & Partner at ACOHA (private practice in New Jersey); fellowship trained at New York Presbyterian-Columbia University Medical Center.
  • Manages ~400 patients with solid tumors and 25 patients with gastroesophageal junction cancer.
  • Lectures widely on Gastrointestinal and Genitourinary malignancies.

Interview Questions
Q1.

What percent of your patients could benefit from upcoming novel drugs? How much need is there for a tetravalent, bispecific innate cell engager such as AFM24?

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Q2.

Could you the mechanism of action behind the drug’s ability to  bind to CD16A on innate immune cells and EGFR, and how that translates into better patient outcomes? Where do you see the benefits of this approach vs standard care?

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Q3.

How likely is it for AFM24 + Atezolizumab 1PR (Gastric) or 1SD (Pancreatic) to become the  preferred method of treatment, based on the recent data?

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Q4.

The company has stated in the past that every patient overexpressing EGFR could be eligible for treatment with AFMD24 irrespective of mutational status. How would you assess that statement?

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