Expert Interview
Discussing Revance Therapeutics’ DaxibotulinumtoxinA in Moderate to severe glabellar lines following PDUFA Approval
Ticker(s): RVNCAn aesthetician with experience in treating glabellar lines.
Please describe your clinical trial practice,how many patients with moderate to severe glabellar lines have you treated, what is the standard of care?
Added By: catalin_adminCould you please comment on Peptide-Formulated Neuromodulators?
Please discuss the results that the approval is based on, how well does the median duration of six months and up to nine months compare to standard practice?
The effect is apparent after utilizing 0.18 ng of core active ingredient in the 40-unit labeled indication for glabellar lines. Could you please comment on this datapoint?
Added By: catalin_adminBased on the Phase 3 data, how likely are you to be using Daxxify in the future?
-74% of subjects achieved a > two-grade improvement in glabellar lines at week 4 per both investigator and patient assessment-88% achieved > two-grade improvement at week 4 per investigator assessment1-98% of subjects achieved none or mild wrinkle severity at week 4 per investigator assessment -6-month median duration-Some patients maintained treatment results at 9 months-Results seen as early as one day after treatment, typically seen within two days
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