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Expert Interview

Slingshot members are talking to an expert! The topic is:

Discussing the potential of Petosemtamab in treating Head and Neck Cancer (HNSCC) and how it compares to other EGFR biologics

Ticker(s): MRUS

Who's the expert?

Institution: MD Anderson 

  • Professor of Medicine Thoracic-Head & Neck Med Oncology at The University of Texas MD Anderson Cancer Center.
  • Manages 20 patients with HNSCC per week.
  • Research focused on defining the biological and molecular effects of the modulation of signal transduction pathways in lung, head and neck, and HPV+ cancers; has defined novel mechanisms of sensitivity and resistance to kinase inhibitors.

Interview Questions
Q1.

Could you first give a brief introduction of your clinical expertise and details about your practice setting?

Added By: ben_admin
Q2.

How many patients with head and neck cancer do you treat? Do you treat any with metastatic disease? What % is metastatic?

Added By: ben_admin
Q3.

What are you typically giving patients right now on the front line? What is your treatment algorithm in making these decisions?

Added By: ben_admin
Q4.

Can you talk about your familiarity with EGFR targeting medications and their efficacies?

Added By: ben_admin
Q5.

Have you prescribed bispecifics (ex. blinatumomab, emicizumab, amivantamab) before and if so in what setting? What has been your experience?

Added By: ben_admin
Q6.

On clinical trials.org, there are no sites yet recruiting in the US. Does this concern you at all for FDA approval moving forward or Merus’ ability to recruit an adequate number of patients?

Added By: ben_admin

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Reason

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