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Expert Interview

Slingshot members are talking to an expert! The topic is:

Examining ImmuityBio's novel therapeutic approach to BCG-unresponsive high grade NMIBC combining Anktiva (N-803) with intravesical BCG and its recent Phase 2/3 QUILT3.032 Trial results presented at ASCO-GU

Ticker(s): IBRX

Who's the expert?

Institution: The University of Calgary

  • Clinical Associate Professor, Departments of Surgery and Oncology, The University of Calgary Medical Director, Clinic for Advanced and Metastatic Prostate Cancer (CAMP), Prostate Cancer Centre.
  • Manages 50 patients with mCRPC and 400 patients with bladder cancer.
  • Specializes in the management of prostate, bladder, and kidney cancer and has expertise in open, laparoscopic, and robotic surgical techniques; sits on the Medical Advisory Board for Kidney Cancer Canada and Bladder Cancer Canada.

Interview Questions
Q1.

Roughly how many patients with NMIBC do you currently manage?

Added By: c_admin
Q2.

On a scale from 1 -10 (10 being extremely excited) where would you rate your level of excitement for Immunity Bio's combo therapy?

Added By: c_admin
Q3.

Will this trial be submitted for regulatory approval? If so, the trial lacks a control arm will this be viewed negatively by FDA and will they require a new Phase 3 trial to be run? For a Phase 3 trial what would be the best active comparator (standard-of-care) to use for the control arm?

Added By: bludvl15
Q4.

Are there any future therapies in the pipeline for which you are excited about?

Added By: bludvl15
Q5.

Have you used pembrolizumab (recently approved for NMIBC) and do you see a place for immuno-oncology agents in high-risk disease?

Added By: bludvl15
Q6.

What is the current standard of care in NMIBC? 

Added By: bludvl15
Q7.

How is the field being impacted by supply shortages of BCG?

Added By: bludvl15
Q8.

What current treatment options are the most utilized by physicians?

Added By: presma02
Q9.

Given this is a combination treatment of N-803 + BCG, will N-803 monotherapy ever be evaluated to understand single-agent efficacy? 

Added By: bludvl15

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