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Expert Interview

Slingshot members are talking to an expert! The topic is:

Discussing Ascendis Pharma A/S’ TransCon hGH for Pediatric Growth Hormone Deficiency, as it receives EMA approval

Ticker(s): ASND

Who's the expert?

A pediatric endocrinologist with experience in treating Pediatric Growth Hormone Deficiency.

Interview Questions
Q1.

Please tell us about your clinical experience. How many patients with hATTR Amyloidosis do you see on a yearly basis? Could you talk about the standard of care for GHD - the daily subcutaneous injection of hGH?

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Q2.

What % of patients achieve good outcomes with standard of care medication?

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Q3.

What advantages do TransCon molecules have? Can you tell us in detail about the interactions of the three components: unmodified parent drug, inert carrier that protects it, and a linker that temporarily binds the two?

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Q4.

Could you please comment on the company’s Phase 3 heiGHt, fliGHt and enliGHten Trials, how convinced are you by the results?

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Q5.

How likely are you to switch patients to Ascendis’ prodrug somatropin formulation? How important is the sustained release of unmodified somatropin (hGH) at predictable therapeutic levels in the body in achieving better outcomes to your patients?

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