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Expert Interview

Slingshot members are talking to an expert! The topic is:

A Second Perspective: Discussing a4b7 integrin blocking in moderate to severe ulcerative colitis: Looking at 1st gen PTG-100 and MORF-057

Ticker(s): MORF, PTGX, TAK

Who's the expert?

Institution: NYU

  • Assistant Professor of Medicine in the Division of Gastroenterology at NYU Grossman School of Medicine & gastroenterologist at the IBD Center at NYU Langone Health.
  • Principal investigator of the institutional NYU IBD biorepository, IBD and Clostridioides difficile clinical trials; manages ~500 patients with ulcerative colitis (150 moderate-severe).
  • Research focuses on IBD epidemiology, pathogenic triggers of IBD onset and flare, and ex vivo models for predicting responsiveness to IBD therapies.

Interview Questions

Roughly how many patients with UC do you currently manage?

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On a scale from 1-10 (10 being extremely excited) where would you rate your level of excitement for PTG-100? For MORF-057?

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If a patient doesn't respond to a4b7 inhibitor, what could be the reason?

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