Expert Interview
Analyzing ImmunoGen’s mirvetuximab in FRalpha,-high platinum-resistant ovarian cancer
Ticker(s): IMGNAn oncologist with experience in treating platinum-resistant ovarian cancer
Please tell us about your clinical experience. How many patients with ovarian cancer do you see on a yearly basis? What is the standard of care and what treatments are available for FRalpha,-high platinum-resistant ovarian cancer ?
What percent of the patients have been previously treated with Avastin, and have not responded well?
What percent of ovarian cancer is folate receptor alpha high?
Added By: slingshot_insightsCould you please discuss the results of the SORAYA study, where:-treatment with mirvetuximab achieved an ORR of 32.4% and 31.6% as assessed by a study investigator and a blinded independent central review. The median duration response was 5.9 months as of the data cut-off date. -Nearly half of responding patients have continued on therapy and the company expects the final median DOR to improve and could range from 5.7 to just above 7 months. -a 10% discontinuation rate.
How likely is this data to be replicated in a follow-up single-arm study?
Could you compare the results to $MRSN’s, with ~35% of patients having 4+ prior lines and the rest 1-3 @ ~34% ORR in napi2b high patients?
How likely would you be to prescribe mirvetuximab for your patients?
Added By: slingshot_insightsAre You Interested In These Questions?
Slingshot Insights Explained
Expert research benefits investors by giving them timely access to unbiased real world perspectives on highly specialized topics. Slingshot Insights' crowdfunded model makes this access available at a fraction of the cost of other expert networks.
Reason
*Slingshot Insights provides access to information, not investment advice. We work to support you and facilitate access to experts; however we are not responsible for monitoring calls for the disclosure of MNPI. You should obtain financial, legal and tax advice from your qualified and licensed advisers before deciding to invest in any security.