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Expert Interview

Slingshot members are talking to an expert! The topic is:

Analyzing ImmunoGen’s mirvetuximab in FRalpha,-high platinum-resistant ovarian cancer

Ticker(s): IMGN

Who's the expert?

An oncologist with experience in treating platinum-resistant ovarian cancer

Interview Questions
Q1.

Please tell us about your clinical experience. How many patients with ovarian cancer do you see on a yearly basis? What is the standard of care and what treatments are available for FRalpha,-high platinum-resistant ovarian cancer ?

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Q2.

What percent of the patients have been previously treated with Avastin, and have not responded well?

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Q3.

What percent of ovarian cancer is folate receptor alpha high?

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Q4.

Could you please discuss the results of the SORAYA study, where:-treatment with mirvetuximab achieved an ORR of 32.4% and 31.6% as assessed by a study investigator and a blinded independent central review. The median duration response was 5.9 months as of the data cut-off date. -Nearly half of responding patients have continued on therapy and the company expects the final median DOR to improve and could range from 5.7 to just above 7 months. -a 10% discontinuation rate.

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Q5.

How likely is this data to be replicated in a follow-up single-arm study?

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Q6.

Could you compare the results to $MRSN’s, with ~35% of patients having 4+ prior lines and the rest 1-3 @ ~34% ORR in napi2b high patients?

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Q7.

How likely would you be to prescribe mirvetuximab for your patients?

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