Expert Interview
Analyzing ImmunoGen’s mirvetuximab in FRalpha,-high platinum-resistant ovarian cancer
Ticker(s): IMGNAn oncologist with experience in treating platinum-resistant ovarian cancer
Please tell us about your clinical experience. How many patients with ovarian cancer do you see on a yearly basis? What is the standard of care and what treatments are available for FRalpha,-high platinum-resistant ovarian cancer ?
What percent of the patients have been previously treated with Avastin, and have not responded well?
What percent of ovarian cancer is folate receptor alpha high?
Added By: catalin_adminCould you please discuss the results of the SORAYA study, where:-treatment with mirvetuximab achieved an ORR of 32.4% and 31.6% as assessed by a study investigator and a blinded independent central review. The median duration response was 5.9 months as of the data cut-off date. -Nearly half of responding patients have continued on therapy and the company expects the final median DOR to improve and could range from 5.7 to just above 7 months. -a 10% discontinuation rate.
How likely is this data to be replicated in a follow-up single-arm study?
Could you compare the results to $MRSN’s, with ~35% of patients having 4+ prior lines and the rest 1-3 @ ~34% ORR in napi2b high patients?
How likely would you be to prescribe mirvetuximab for your patients?
Added By: catalin_adminAre You Interested In These Questions?
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