Make Informed Investment Decisions with Affordable Access to Experts
A discussion on the Phase V Research report released on Linzess adverse events and poor patient experience. There will be a focus on the FAERS reported deaths & if they are more likely disease or drug relatedTicker(s): IRWD, AGN, SGYP
Name: Dr Philip Schoenfeld - MD
Institution: Detroit VA Medical Center
- Chief of Gastroenterology at the Detroit VA medical center and previous Director of Gastrointestinal Epidemiology and Professor of Medicine at University of Michigan
- Co-authored the American College of Gastroenterology’s Guideline on Colon Cancer Screening and the American College of Gastroenterology/American Society for Gastrointestinal Endoscopy Position Statement on Quality Indicators in Colonoscopy
- Has published more than 100 original research studies in peer-reviewed journals and past Associate Editor (Colon) for American Journal of Gastroenterology; has served on the editorial boards of Alimentary Pharmacology and Therapeutics and Journal of Clinical Gastroenterology
How has your experience treating patients with Linzess been? Do the points of patient issues highlighted in the Phase V Research report sound representative of your experience?
Looking at the deaths in the FAERS database, what impact does that have on your opinion of the drug?
A specific case of death following fecal vomiting was highlighted in the Phase V report. Does this sound potentially drug related or is it a potential outcome of severe IBS-C?
Why was immunogenicity never talked about by the company? What do physicians think about this?Added By: katyand
Do you think there is enough evidence at this point to suggest that Linzess is acting systemically?What would be the implications of a systemic action by Linzess?Added By: katyand
Have you rendered services to Ironwood (such as consulting, etc)? Have you received payment from Ironwood and if yes, in what form and for which services? Have you interacted with the company in the past week?
If Linzess is having severe issue in the real world, how much of a read across does this have for plecanatide? Is this a net positive or negative in your mind for plecanatide?
How much of an advantage is Plecanatide's lower diarrhea rate compared to Linzness? Would you be more likely to prescribe Plecanatide based on fewer side effects?Added By: biocourseinc
What has your experience been working with Synergy compared to other companies?Added By: biocourseinc
Slingshot Insights Explained
Expert research benefits investors by giving them timely access to unbiased real world perspectives on highly specialized topics. Slingshot Insights' crowdfunded model makes this access available at a fraction of the cost of other expert networks.