Expert Interview
Examining BioLineRx’s Motixafortide in Second Line Metastatic Pancreatic Cancer, With recent COMBAT/KEYNOTE-202 Phase 2a Data to Discuss
Ticker(s): BLRXAn oncologist with experience in treating metastatic pancreatic cancer
Please tell us about your experience as a physician. How many patients with pancreatic cancer do you see yearly? What % of patients do you treat with metastatic form?
Added By: slingshot_insightsWhat is the second-line of treatment that you’re currently using? How has your approach changed in recent years?
Added By: slingshot_insightsCan you comment on the mechanism of action for motixafortide, how it acts as an inverse agonist of CXCR4 and your view on the high-affinity, long receptor occupancy?
Added By: slingshot_insightsWhat treatment do you switch over to, for liver failure following metastasis?
Added By: slingshot_insightsWhat is your choice of treatment follow-up for unresectable stage IV metastatic PDAC patients, who had progressed following first-line gemcitabine-based therapy? What are the pros and cons, and how would motixafortide fit in the picture?
Added By: slingshot_insightsIs the 2 months survival gain what data usually looks like for pancreatic cancer? How do the Keynote arm median overall survival compare to other treatment options?
Added By: slingshot_insightsCan you comment on the disease control rate of 63.2% for motixafortide?
Added By: slingshot_insightsHow much of a need is there for this type of treatment? What are your hopes for the future? Are you optimistic about anything in particular?
Added By: slingshot_insightsHow likely would you be to use motixafortide in your practice, as second-line therapy?
Added By: slingshot_insightsAre You Interested In These Questions?
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