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Additional Relevant Details Update on Aug 30 2017: Abstract from the MN-166 (ibudilast) SPRINT-MS Phase 2b Study in Progressive MS - including Top Line Data - was Selected as a Platform Presentation for Late-Breaking Presentation at the 7th Joint ECTRIMS - ACTRIMS Meeting on October 28, 2017 in Paris, France

http://investors.med...

Clinical Data Update on Oct 30 2017:Primary Endpoint #1: MN-166 (ibudilast) demonstrated a statistically significant 48% reduction in the rate of progression of whole brain atrophy compared to placebo (p=0.04) as measured by MRI analysis using brain parenchymal fraction (BPF).Primary Endpoint #2: MN-166 (ibudilast) demonstrated a favorable safety and tolerability profile. There was not an increased rate of serious adverse events in the MN-166 (ibudilast) group compared to the placebo group. There were no opportunistic infections, no cancers, no cardiovascular events (i.e. no heart attacks or strokes), and no deaths related to MN-166 (ibudilast) treatment, as determined by an Independent Medical Monitor. There was no statistically significant difference in tolerability between the MN-166 (ibudilast) group and the placebo group. The most common treatment-emergent adverse events during the study were gastrointestinal adverse events, which occurred with a higher frequency in the MN-166 (ibudilast) group, and upper respiratory tract infections, which occurred with a higher frequency in the placebo group.

http://investors.med...

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