Catalyst
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Phase 2 data of R348 for Chronic dry eye disease - as a result of patients with acute or chronic graft vs. host disease due 2016
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Additional Information
R348—Dry Eye in Patients with Ocular Graft-Versus-Host Disease (GvHD)
Disease background. According to an article published by the American Academy of Ophthalmology, a significant number (22% to 80%) of patients with acute or chronic GvHD develop a secondary incidence of dry eye (keratoconjunctivitis sicca). In general, these patients are severely ill and have a great medical need for a topical therapy that may better manage their symptoms.
Topical Ophthalmic JAK/SYK inhibitor program. R348, a topical ophthalmic JAK/SYK inhibitor, is being evaluated in a Phase 2 clinical trial of patients with ocular GvHD to determine if it reduces inflammation and limits the damage to the eye tissue caused by the disease. We expect results of this clinical trial in 2016.
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Catalyst Date
Occurred on:
Jul 12, 2016
Occurred Source:
https://clinicaltrials.gov/archive/NCT02040623/2016_07_12/changes
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Related Keywords
Phase 2 Data, R348, Chronic Dry Eye Disease, Graft Vs Host Disease, Gvhd