Management Comment “Now that we have received regulatory feedback, we have initiated preparations for a Phase 3 trial of MarzAA in individuals with hemophilia A or B with inhibitors,” said Nassim Usman, Ph.D., president and chief executive officer of Catalyst. “We plan to enroll the first patient before year end, however that date is dependant on the readiness of our trial sites and improvements in the current effects of COVID-19 on clinical trial execution. At present, manufacturing and drug supply are unaffected for our clinical trials.”