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Xenon Pharma (XENE) Expected to file an investigational new drug (IND) application or XEN901, a selective inhibitor of Nav1.6 for the treatment of epilepsy disorders in the first half of 2017

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  • XEN901 is a potent, selective Nav1.6 inhibitor for the treatment of rare infantile epileptic encephalopathies and other forms of epilepsy. XEN901 has demonstrated efficacy against seizures in an animal model of Nav1.6 gain-of-function SCN8A epilepsy as well as models that support the treatment of adult partial onset epilepsy. Xenon expects to file an investigational new drug (IND), or IND equivalent, application in the fourth quarter of 2017.
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Occurred on:
Dec 04, 2017
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Related Keywords Xen901, Nav1.6, Eplilepsy, Gdc-0310