Additional Relevant Details The initial study, which took place from March to May of 2016, was a multi-site study, involving 433 piglets, from two age groups (1-3 days and 10-15 days), that had a history of diarrhea. The piglets were either placed in a treatment group in which they were individually treated with 10-20 mg of Neonorm™ powder in a water formulation twice daily for three days or placed in a control group.
In the groups of piglets aged 1-3 days, 99% achieved resolution of diarrhea following Neonorm™ treatment versus no resolution in the control group. There was a 3% mortality in the Neonorm™ group, while the control group had 100% mortality. In the group of piglets aged 10-15 days, the rate of diarrhea resolution was 70%, versus no resolution in the control group; mortality was 30% versus 100%, respectively. Comparisons of diarrhea resolution and mortality rates between the Neonorm™-treated group and control groups generated p-values less than 0.01.The second study was initiated in June of this year at a farm in China that had just experienced an outbreak of Porcine Epidemic Diarrhea Virus (PEDv). Piglets at this farm were divided into three treatment groups with no control and received 8-20 mg of Neonorm™. The 200 piglets placed in treatment group A were all suffering from diarrhea caused by PEDv. The 200 piglets in treatment group B had recently contracted PEDv, and received a lower dose of Neonorm™.  The 100 piglets in treatment group C were healthy and were treated prophylactically.The results of the second study demonstrate a 95% cure rate among piglets in group A, who received 10-20 mg of Neonorm™ administered over two days. The cure rate in group B among piglets that received 8-16 mg of Neonorm™ for three days was 60%. At this farm, a mortality rate of 50% is typically seen in piglets diagnosed with PEDv. Group C was treated prophylactically with 8-16 mg of Neonorm for three days and 15% developed diarrheal symptoms, which is similar to the usual frequency at this farm without prophylactic treatment.