Management Comment “We are very excited to receive FDA approval for Akovaz, the third product from our Éclat portfolio, and in line with the PDUFA date expectations. Revenue expectations associated with this product were included in our previously issued 2016 revenue guidance of $110 - $130 million. Our Éclat portfolio of products, which includes Bloxiverz® and Vaculep®, has produced significant cash flow for Flamel, allowing usto operate independently of partners, fund strategic acquisitions and continue development of our proprietary pipeline products,” said Mike Anderson, Chief Executive Officer of Flamel.