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Agios Pharma (AGIO) to complete Phase 1/2 Study of AG-221 in Subjects with Hematologic Malignancies with an IDH2 Mutation in September 2017

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Additional Information

Additional Relevant Details An ongoing Phase 1 trial that includes a dose-escalation phase, four expansion cohorts of 25 patients each and a Phase 2 expansion cohort of 125 patients with IDH2 mutant-positive AML who are in second or later relapse, refractory to second-line induction or reinduction treatment, or have relapsed after allogeneic transplantation. The primary objectives of the study are to confirm the safety and clinical activity of AG-221 in a select, highly resistant AML population
http://www.agios.com...
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Related Keywords Phase 1/2 Study, Ag-221, Hematologic Malignancies, Idh2 Mutation, Open Label